产品名称 Anti-EEA1抗体 参阅全部 EEA1 一抗
特异性 ab123380 detects endogenous levels of EEA1.
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Mouse, Rat, Human
Synthetic peptide conjugated to KLH, corresponding to a region surrounding amino acids 12-16 (
RVGSQ ) of Human EEA1.
Jurkat and HL60 cell extracts.
存放说明 Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
存储溶液 pH: 7.40 Preservative: 0.02% Sodium azide Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride Note: (without Mg2+ and Ca2+)
Concentration information loading...
纯度 Immunogen affinity purified
纯化说明 ab123380 was purified by affinity-chromatography using epitope-specific peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 170 kDa (predicted molecular weight: 162 kDa).
功能 Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
序列相似性 Contains 1 C2H2-type zinc finger. Contains 1 FYVE-type zinc finger.
结构域 The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate in membranes of early endosomes and penetrates bilayers. The FYVE domain insertion into PtdIns(3)P-enriched membranes is substantially increased in acidic conditions.
细胞定位 Cytoplasm. Early endosome membrane.
Information by UniProt
Early endosome antigen 1 antibody
Early endosome antigen 1, 162kD antibody
Early endosome associated protein antibody
Anti-EEA1 antibody (ab123380)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"