Anti-EDG8抗体- Aminoterminal end (ab60039)


  • 产品名称Anti-EDG8抗体- Aminoterminal end
    参阅全部 EDG8 一抗
  • 描述
    兔多克隆抗体to EDG8 - Aminoterminal end
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (10-30 aa in length) at the N-terminal of first 50 aa of human EDG8 conjugated to KLH

  • 阳性对照
    • Human hepatocarcinoma tissue.



Our Abpromise guarantee covers the use of ab60039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
IHC-P 1/50 - 1/100.


  • 功能Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
  • 组织特异性Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overexpressed in leukemic large granular lymphocytes. Isoform 1 is predominantly expressed in peripheral tissues. Isoform 2 is expressed in brain, spleen and peripheral blood leukocytes.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 发展阶段At 24 weeks of gestation, fragments of radial glial fibers are positive within the cortical plate and subplate of allocortical areas. These positive fragments often appear enlarged as varicosities and some of them terminate at blood vessels. Between 28 and 30 weeks of gestation, all iso- and allocortical areas contain immunolabelled radial glial fibers revealing curvature next to sulci. After 32 weeks of gestation, radial glial fibers gradually disappear; instead positive transitional stages between radial glia and astrocytes were found.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EDG 8 antibody
    • EDG8 S1P receptor antibody
    • Endothelial differentiation G protein coupled receptor 8 antibody
    • Endothelial differentiation G-protein-coupled receptor 8 antibody
    • Endothelial Differentiation Gene 8 antibody
    • Endothelial differentiation sphingolipid G protein coupled receptor 8 antibody
    • S1P receptor 5 antibody
    • S1P receptor Edg 8 antibody
    • S1P receptor Edg-8 antibody
    • S1P receptor Edg8 antibody
    • S1P5 antibody
    • S1PR5 antibody
    • S1PR5_HUMAN antibody
    • Sphingosine 1 Phosphate Receptor 5 antibody
    • Sphingosine 1 phosphate receptor Edg 8 antibody
    • Sphingosine 1 phosphate receptor Edg8 antibody
    • Sphingosine 1-phosphate receptor 5 antibody
    • Sphingosine 1-phosphate receptor Edg-8 antibody
    • SPPR 1 antibody
    • SPPR 2 antibody
    • SPPR1 antibody
    • SPPR2 antibody
    see all

Anti-EDG8 antibody - Aminoterminal end 图像

  • ab60039 at 1/50 dilution staining EDG8 in Human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. A peroxidase-conjugated secondary antibody was used, followed by AEC staining.

Anti-EDG8 antibody - Aminoterminal end (ab60039)参考文献

ab60039 has not yet been referenced specifically in any publications.

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