概述

  • 产品名称Anti-EDG6抗体
    参阅全部 EDG6 一抗
  • 描述
    兔多克隆抗体to EDG6
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cow, Dog, Pig, Macaque Monkey, Gorilla
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Human EDG6.

  • 阳性对照
    • This antibody gave a positive signal in Jurkat whole cell lysate as well as the following tissue lysates: Human Spleen; Human Tonsil; Human Lymph node.

性能

应用

Our Abpromise guarantee covers the use of ab92993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 42 kDa).

靶标

  • 功能Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
  • 组织特异性Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EDG6 antibody
    • Endothelial differentiation lysophosphatidic acid G protein coupled receptor 6 antibody
    • Endothelial differentiation G protein coupled receptor 6 antibody
    • Endothelial differentiation G-protein coupled receptor 6 antibody
    • Endothelial differentiation gene 6 antibody
    • LPC1 antibody
    • Lysophospholipid receptor C1 antibody
    • MGC129298 antibody
    • Putative G protein coupled receptor antibody
    • S1P receptor 4 antibody
    • S1P receptor Edg-6 antibody
    • S1P receptor Edg6 antibody
    • S1P4 antibody
    • S1PR4 antibody
    • S1PR4_HUMAN antibody
    • SLP4 antibody
    • Sphingosine 1 phosphate receptor 4 antibody
    • Sphingosine 1 phosphate receptor Edg6 antibody
    • Sphingosine 1-phosphate receptor 4 antibody
    • Sphingosine 1-phosphate receptor Edg-6 antibody
    see all

Anti-EDG6 antibody 图像

  • All lanes : Anti-EDG6 antibody (ab92993) at 1 µg/ml

    Lane 1 : Human spleen tissue lysate - total protein (ab29699)
    Lane 2 : Tonsil (Human) Tissue Lysate
    Lane 3 : Human lymph node tissue lysate - total protein (ab29871)
    Lane 4 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 42 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 56 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 12 minutes

Anti-EDG6 antibody (ab92993)参考文献

ab92993 has not yet been referenced specifically in any publications.

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