概述

  • 产品名称Anti-EDG3抗体[EPR4540(2)]
    参阅全部 EDG3 一抗
  • 描述
    兔单克隆抗体[EPR4540(2)] to EDG3
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human EDG3 aa 1-100 (N terminal).

  • 阳性对照
    • MCF-7 cell lysate, HepG2 cell lysate, 293T cell lysate, JAR cell lysate.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab108370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/10000 - 1/50000. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
    • 组织特异性Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
    • 序列相似性Belongs to the G-protein coupled receptor 1 family.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • EDG 3 antibody
      • EDG3 antibody
      • Endothelial differentiation G protein coupled receptor 3 antibody
      • Endothelial differentiation G-protein coupled receptor 3 antibody
      • Endothelial differentiation gene 3 antibody
      • Endothelial differentiation sphingolipid G protein coupled receptor 3 antibody
      • FLJ37523 antibody
      • FLJ93220 antibody
      • G protein coupled receptor endothelial differentiation gene 3 antibody
      • LPB 3 antibody
      • LPB3 antibody
      • MGC71696 antibody
      • OTTHUMP00000215691 antibody
      • S1P receptor 3 antibody
      • S1P receptor Edg 3 antibody
      • S1P receptor Edg-3 antibody
      • S1P receptor EDG3 antibody
      • S1P3 antibody
      • S1pr3 antibody
      • S1PR3_HUMAN antibody
      • Sphingosine 1 phosphate receptor 3 antibody
      • Sphingosine 1 phosphate receptor Edg 3 antibody
      • Sphingosine 1 phosphate receptor Edg3 antibody
      • Sphingosine 1-phosphate receptor 3 antibody
      • Sphingosine 1-phosphate receptor Edg-3 antibody
      see all

    Anti-EDG3 antibody [EPR4540(2)] 图像

    • All lanes : Anti-EDG3 antibody [EPR4540(2)] (ab108370) at 1/10000 dilution

      Lane 1 : MCF-7 cell lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : JAR cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 42 kDa

    Anti-EDG3 antibody [EPR4540(2)] (ab108370)参考文献

    This product has been referenced in:
    • Guan Z  et al. Sphingosine-1-Phosphate Evokes Unique Segment-Specific Vasoconstriction of the Renal Microvasculature. J Am Soc Nephrol N/A:N/A (2014). Read more (PubMed: 24578134) »
    • Arana L  et al. Ceramide 1-phosphate induces macrophage chemoattractant protein-1 release: involvement in ceramide 1-phosphate-stimulated cell migration. Am J Physiol Endocrinol Metab 304:E1213-26 (2013). Read more (PubMed: 23548612) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"