概述

性能

应用

Our Abpromise guarantee covers the use of ab54948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.
    • 组织特异性Endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin.
    • 序列相似性Belongs to the G-protein coupled receptor 1 family.
    • 翻译后修饰S1P-induced endothelial cell migration requires the PKB/AKT1-mediated phosphorylation of the third intracellular loop at the Thr-236 residue.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD363 antibody
      • CHEDG 1 antibody
      • CHEDG1 antibody
      • D1S3362 antibody
      • ECGF 1 antibody
      • ECGF1 antibody
      • EDG 1 antibody
      • EDG1 antibody
      • endothelial differentiation G protein coupled receptor 1 antibody
      • Endothelial differentiation G-protein coupled receptor 1 antibody
      • Endothelial differentiation sphingolipid G protein coupled receptor 1 antibody
      • FLJ58121 antibody
      • G protein coupled sphingolipid receptor antibody
      • g protein-coupled receptor edg-1 antibody
      • S1P receptor 1 antibody
      • S1P receptor Edg 1 antibody
      • S1P receptor Edg-1 antibody
      • S1P receptor Edg1 antibody
      • S1P(1) receptor antibody
      • S1P1 antibody
      • s1pr1 antibody
      • S1PR1_HUMAN antibody
      • sphingolipid g-protein-coupled receptor 1 antibody
      • Sphingosine 1 phosphate receptor Edg 1 antibody
      • Sphingosine 1 phosphate receptor EDG1 antibody
      • sphingosine 1- phosphate receptor 1 antibody
      • Sphingosine 1-phosphate receptor 1 antibody
      • Sphingosine 1-phosphate receptor Edg-1 antibody
      • Sphingosine 1phosphate receptor type 1 S1P1 antibody
      see all

    Anti-EDG1 antibody 图像



    • Predicted band size : 43 kDa
      EDG1 antibody (ab54948) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

    Anti-EDG1 antibody (ab54948)参考文献

    ab54948 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"