概述

  • 产品名称Anti-ECE2抗体
    参阅全部 ECE2 一抗
  • 描述
    兔多克隆抗体to ECE2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 280-329 (YMVELGMLLG GQPTSTRAQM QQVLELEIQL ATITVPQDQR RDEEKIYHKM) of Rat ECE2 (NP_001002815).

  • 阳性对照
    • Rat Brain Lysate.

性能

应用

Our Abpromise guarantee covers the use of ab110725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
  • 组织特异性Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level).
  • 序列相似性In the N-terminal section; belongs to the methyltransferase superfamily.
    In the C-terminal section; belongs to the peptidase M13 family.
  • 细胞定位Golgi apparatus membrane. Cytoplasmic granule membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ECE 2 antibody
    • ECE-2 antibody
    • ECE2 antibody
    • ECE2_HUMAN antibody
    • Endothelin converting enzyme 2 antibody
    • Endothelin-converting enzyme 2 region antibody
    • Hypothetical protein MGC2408 antibody
    • KIAA0604 antibody
    • MGC17664 antibody
    • MGC78487 antibody
    see all

Anti-ECE2 antibody 图像

  • Anti-ECE2 antibody (ab110725) at 1 µg/ml + Rat Brain Lysate at 10 µg

    Predicted band size : 86 kDa

Anti-ECE2 antibody (ab110725)参考文献

ab110725 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110725.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"