概述

  • 产品名称Anti-EBP1抗体
    参阅全部 EBP1 一抗
  • 描述
    兔多克隆抗体to EBP1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide selected from the center region of human EBP1 conjugated to KLH (NP_006182)

  • 阳性对照
    • Jurkat cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab82858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).
ELISA 1/1000.

靶标

  • 功能May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site).
  • 组织特异性Expressed in several cell lines tested, including primary and transformed cell lines.
  • 序列相似性Belongs to the peptidase M24 family.
  • 翻译后修饰Phosphorylated on serine and threonine residues. Phosphorylation is enhanced by HRG treatment. Basal phosphorylation is PKC-dependent and HRG-induced phosphorylation is predominantly PKC-independent.
  • 细胞定位Cytoplasm. Nucleus > nucleolus. Tranlocates to the nucleus upon treatment with HRG.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 38kDa antibody
    • AA672939 antibody
    • Cell cycle protein p38 2G4 homolog antibody
    • Cell cycle protein p38-2G4 homolog antibody
    • ErbB-3 binding protein 1 antibody
    • ErbB3 binding protein 1 antibody
    • ErbB3-binding protein 1 antibody
    • ErbB3-binding protein Ebp1 antibody
    • hG4 1 antibody
    • hG4-1 antibody
    • IRES-specific cellular trans-acting factor 45 kDa antibody
    • MGC81621 antibody
    • MGC94070 antibody
    • Mpp1 antibody
    • p38 2G4 antibody
    • Pa2g4 antibody
    • PA2G4_HUMAN antibody
    • Plfap antibody
    • Proliferation associated 2G4 antibody
    • Proliferation associated 2G4, 38-KD antibody
    • Proliferation-associated 2G4, 38kDa antibody
    • Proliferation-associated 2G4, a antibody
    • Proliferation-associated protein 1 antibody
    • Proliferation-associated protein 2G4 antibody
    • Protein p38-2G4 antibody
    • si:dz150i12.2 antibody
    • wu:fb19b11 antibody
    • wu:ft56d05 antibody
    • zgc:86732 antibody
    see all

Anti-EBP1 antibody 图像

  • Anti-EBP1 antibody (ab82858) at 1/50 dilution + Jurkat cell line lysates at 35 µg

    Predicted band size : 44 kDa
    Observed band size : 44 kDa
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

Anti-EBP1 antibody (ab82858)参考文献

ab82858 has not yet been referenced specifically in any publications.

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