概述

  • 产品名称Anti-Ebola virus抗体[FE25]
    参阅全部 Ebola virus 一抗
  • 描述
    小鼠单克隆抗体[FE25] to Ebola virus
  • 特异性Ebola virus, Zaire strain
  • 经测试应用适用于: ICC/IF, ELISAmore details
    不适用于: WB
  • 免疫原

    Formalin inactivated Ebola virus (strain Zaire).

  • 常规说明Concentration varies from lot to lot and can be provided on request.


    Ebola virus is an enveloped, negative-stranded RNA virus. This virus belongs to the family Filoviridae and has a distinctive morphology similar only to that of Marburg virus, but apparently has no antigenic characteristics of Marburg virus. Its genome is a nonsegmented RNA strand. SDS-PAGE profiles demonstrate the presence of seven structural proteins. These are the major nucleoprotein NP (104 K), glycoprotein GP (125K), L protein (180 K), and four proteins: VP40 (40 K), ‘V’PX (35 K), VP30 (30 K) and VP24 (24 K). All the proteins are encoded by monocistronic mRNA transcripts complementary to virion RNA. GP is the major protein of the surface spikes and only this 125K viral protein is glycosylated.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明Purity tested by electrophoresis.
  • Primary antibody说明Ebola virus is an enveloped, negative-stranded RNA virus. This virus belongs to the family Filoviridae and has a distinctive morphology similar only to that of Marburg virus, but apparently has no antigenic characteristics of Marburg virus. Its genome is a nonsegmented RNA strand. SDS-PAGE profiles demonstrate the presence of seven structural proteins. These are the major nucleoprotein NP (104 K), glycoprotein GP (125K), L protein (180 K), and four proteins: VP40 (40 K), ‘V’PX (35 K), VP30 (30 K) and VP24 (24 K). All the proteins are encoded by monocistronic mRNA transcripts complementary to virion RNA. GP is the major protein of the surface spikes and only this 125K viral protein is glycosylated.
  • 克隆单克隆
  • 克隆编号FE25
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab1924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration. PubMed: 25815346
ELISA Use at an assay dependent concentration.
  • 应用说明Is unsuitable for WB.
  • Anti-Ebola virus antibody [FE25] (ab1924)参考文献

    This product has been referenced in:
    • Dowall SD  et al. Effective binding of a phosphatidylserine-targeting antibody to Ebola virus infected cells and purified virions. J Immunol Res 2015:347903 (2015). ICC/IF . Read more (PubMed: 25815346) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. The immunogen for ab1924, Ebola virus antibody [FE25] was a Formalin inactivated Ebola virus (strain Zaire) preparation. Unfortunately the protein target and epitope have not yet been characterized. I hope this infor...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"