概述

  • 产品名称Anti-EB3抗体
    参阅全部 EB3 一抗
  • 描述
    山羊多克隆抗体to EB3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Horse, Cow, Dog
  • 免疫原

    Synthetic peptide:

    SGRLSNVAPPCILR

    , corresponding to internal sequence amino acids 172-185 of Human EB3 (NP_036458.2).

  • 阳性对照
    • Human Brain (Cerebellum and Amygdala) and Mouse Brain lysates

性能

应用

Our Abpromise guarantee covers the use of ab99287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 1 µg/ml. Predicted molecular weight: 32 kDa.

靶标

  • 功能May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
  • 组织特异性Predominantly expressed in brain and muscle.
  • 序列相似性Belongs to the MAPRE family.
    Contains 1 CH (calponin-homology) domain.
    Contains 1 EB1 C-terminal domain.
  • 结构域Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
  • 细胞定位Cytoplasm > cytoskeleton. Associated with the microtubule network.
  • Information by UniProt
  • 数据库链接
  • 别名
    • APC binding protein antibody
    • EB 3 antibody
    • EB1 protein family member 3 antibody
    • EB3 antibody
    • EBF 3 antibody
    • EBF3 antibody
    • EBF3 S antibody
    • End binding protein 3 antibody
    • End-binding protein 3 antibody
    • MAPRE 3 antibody
    • MAPRE3 antibody
    • MARE3_HUMAN antibody
    • Member 3 antibody
    • Microtubule Associated Protein antibody
    • Microtubule associated protein RP/EB family member 3 antibody
    • Microtubule-associated protein RP/EB family member 3 antibody
    • OTTHUMP00000200910 antibody
    • RP 3 antibody
    • RP/EB Family antibody
    • RP3 antibody
    see all

Anti-EB3 antibody 图像

  • Anti-EB3 antibody (ab99287) at 0.3 µg/ml + Mouse brain lysates at 35 µg

    Predicted band size : 32 kDa
  • Anti-EB3 antibody (ab99287) at 0.1 µg/ml + Human brain (amygdala) lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 32 kDa
    Primary incubation was 1 hour.

Anti-EB3 antibody (ab99287)参考文献

This product has been referenced in:
  • Oz S  et al. The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins. Mol Psychiatry 19:1115-24 (2014). Read more (PubMed: 25178163) »

See 1 Publication for this product

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