概述

  • 产品名称Anti-EB2抗体[K52]
    参阅全部 EB2 一抗
  • 描述
    大鼠单克隆抗体[K52] to EB2
  • 特异性This antibody is specific for EB2 proteins.
  • 经测试应用适用于: WB, ELISA, IP, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Hamster, Human
  • 免疫原

    Recombinant full length EB2 protein (Human)

  • 阳性对照
    • CHO cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab45767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 36 kDa.
ELISA 1/2000 - 1/5000.
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

靶标

  • 功能May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
  • 组织特异性Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
  • 序列相似性Belongs to the MAPRE family.
    Contains 1 CH (calponin-homology) domain.
    Contains 1 EB1 C-terminal domain.
  • 结构域Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
  • 细胞定位Cytoplasm > cytoskeleton. Associated with the microtubule network. Accumulates at the plus end of microtubules.
  • Information by UniProt
  • 数据库链接
  • 别名
    • APC binding protein EB1 antibody
    • APC binding protein EB2 antibody
    • APC-binding protein EB2 antibody
    • EB1 antibody
    • EB2 antibody
    • End binding protein 2 antibody
    • End-binding protein 2 antibody
    • H.sapiens mRNA for novel T cell activation protein antibody
    • MAPRE2 antibody
    • MARE2_HUMAN antibody
    • Microtubule associated protein RP/EB family member 2 antibody
    • Microtubule-associated protein RP/EB family member 2 antibody
    • RP1 antibody
    • T cell activation protein EB1 family antibody
    see all

Anti-EB2 antibody [K52] 图像

  • Immunofluorescence staining of EB2 in CHO cells transfected with EB2 gene expression constructs.

Anti-EB2 antibody [K52] (ab45767)参考文献

This product has been referenced in:
  • Asanov A  et al. A relay mechanism between EB1 and APC facilitate STIM1 puncta assembly at endoplasmic reticulum-plasma membrane junctions. Cell Calcium 54:246-56 (2013). Read more (PubMed: 23871111) »

See 1 Publication for this product

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