Anti-E74 like factor 1抗体(ab64937)

概述

  • 产品名称Anti-E74 like factor 1抗体
    参阅全部 E74 like factor 1 一抗
  • 描述
    兔多克隆抗体to E74 like factor 1
  • 特异性ab64937 detects endogenous levels of total E74 like factor 1 protein.
  • 经测试应用适用于: ELISA, ICC/IF, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human) from the C terminal region.

  • 阳性对照
    • A549 cells and cell extracts from 293 and HuvEc cells.

性能

应用

Our Abpromise guarantee covers the use of ab64937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.
WB 1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).

靶标

  • 功能Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
  • 组织特异性In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
  • 序列相似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • E74 like factor 1 antibody
    • E74-like factor 1 antibody
    • ELF 1 antibody
    • ELF1 antibody
    • ELF1_HUMAN antibody
    • Ets domain transcription factor antibody
    • ETS related transcription factor Elf 1 antibody
    • ETS related transcription factor Elf1 antibody
    • ets-related transcription factor antibody
    • ETS-related transcription factor Elf-1 antibody
    • mElf 1 antibody
    • p70 antibody
    • Sts1 antibody
    • TRANSCRIPTION FACTOR ELF 1 antibody
    see all

Anti-E74 like factor 1 antibody 图像

  • This image shows A549 cells stained with ab64937 at 1/500 dilution; with and without the immunising peptide.
  • All lanes : Anti-E74 like factor 1 antibody (ab64937) at 1/500 dilution

    Lane 1 : extracts from 293 cells (5-30µg total protein)
    Lane 2 : extracts from HuvEc cells (5-30µg total protein)
    Lane 3 : extracts from HuvEc cells (5-30µg total protein) and 5-10µg of the immunising peptide.


    Predicted band size : 67 kDa
    Observed band size : 67 kDa

Anti-E74 like factor 1 antibody (ab64937)参考文献

ab64937 has not yet been referenced specifically in any publications.

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