Anti-E74 like factor 1抗体(ab11801)

概述

  • 产品名称Anti-E74 like factor 1抗体
    参阅全部 E74 like factor 1 一抗
  • 描述
    山羊多克隆抗体to E74 like factor 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide: AMKQNELLEPNSF, corresponding to amino acids 607-619 of Human ELF1.

  • 阳性对照
    • WB: Human tonsil, human lymph node and mouse thymus tissue lysates and Jurkat cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab11801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 65 kDa).

靶标

  • 功能Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
  • 组织特异性In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
  • 序列相似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • E74 like factor 1 antibody
    • E74-like factor 1 antibody
    • ELF 1 antibody
    • ELF1 antibody
    • ELF1_HUMAN antibody
    • Ets domain transcription factor antibody
    • ETS related transcription factor Elf 1 antibody
    • ETS related transcription factor Elf1 antibody
    • ets-related transcription factor antibody
    • ETS-related transcription factor Elf-1 antibody
    • mElf 1 antibody
    • p70 antibody
    • Sts1 antibody
    • TRANSCRIPTION FACTOR ELF 1 antibody
    see all

Anti-E74 like factor 1 antibody 图像

  • All lanes : Anti-E74 like factor 1 antibody (ab11801) at 0.3 µg/ml

    Lane 1 : Human lymph node lysate in RIPA buffer
    Lane 2 : Human tonsil lysate in RIPA buffer
    Lane 3 : Mouse thymus lysate in RIPA buffer

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique

    Predicted band size : 65 kDa

    Incubated with the primary antibody for 1 hour.

  • Anti-E74 like factor 1 antibody (ab11801) at 0.1 µg/ml + Jurkat cell lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 65 kDa

    Incubated with the primary antibody for 1 hour.

Anti-E74 like factor 1 antibody (ab11801)参考文献

ab11801 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I appreciate you highlighting this to me. I can confirm that you are correct. This antibody is in fact associated with the wrong ELF1 target and targets ELF1 (NM_172373; E74 like factor 1). I have amended this on the dat...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"