概述

  • 产品名称
  • 描述
    兔多克隆抗体to E2F7
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 590-619 of Human E2F7.

  • 阳性对照
    • A2058 cell line lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab123864 was purified through a Protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 100 kDa.

靶标

  • 功能
    Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity). Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
  • 序列相似性
    Belongs to the E2F/DP family.
  • 结构域
    Both DNA-binding domains are required for DNA-binding and are proposed to form an intramolecular structure that is similar to the winged helix structure of the E2F-DP heterodimer.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 形式
    There are 2 isoforms produced by alternative splicing.
  • 别名
    • E2F 7 antibody
    • E2F transcription factor 7 antibody
    • E2F-7 antibody
    • E2f7 antibody
    • E2F7_HUMAN antibody
    • FLJ12981 antibody
    • Transcription factor E2F7 antibody
    see all

Anti-E2F7 antibody 图像

  • Anti-E2F7 antibody (ab123864) at 1/100 dilution + A2058 cell line lysate at 35 µg

    Predicted band size : 100 kDa

实验方案

Anti-E2F7 antibody (ab123864)参考文献

ab123864 has not yet been referenced specifically in any publications.

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