概述

  • 产品名称Anti-E2F7抗体
    参阅全部 E2F7 一抗
  • 描述
    山羊多克隆抗体to E2F7
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    C-DLSKQKKFTPERNP

    , corresponding to amino acids 53-66 of Human E2F7 (NP_976328.2).

  • 阳性对照
    • Human kidney, testis, heart and brain cerebellum lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106832 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 100 kDa).

靶标

  • 功能Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity). Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
  • 序列相似性Belongs to the E2F/DP family.
  • 结构域Both DNA-binding domains are required for DNA-binding and are proposed to form an intramolecular structure that is similar to the winged helix structure of the E2F-DP heterodimer.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 形式There are 2 isoforms produced by alternative splicing.
  • 别名
    • E2F 7 antibody
    • E2F transcription factor 7 antibody
    • E2F-7 antibody
    • E2f7 antibody
    • E2F7_HUMAN antibody
    • FLJ12981 antibody
    • Transcription factor E2F7 antibody
    see all

Anti-E2F7 antibody 图像

  • Anti-E2F7 antibody (ab106832) at 0.1 µg/ml + Human kidney lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 100 kDa
    Observed band size : 100 kDa


    Exposure time : 1 hour

Anti-E2F7 antibody (ab106832)参考文献

ab106832 has not yet been referenced specifically in any publications.

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