Anti-E2F4抗体[SPM179], prediluted (ab54168)

概述

  • 产品名称Anti-E2F4抗体[SPM179], prediluted
    参阅全部 E2F4 一抗
  • 描述
    小鼠单克隆抗体[SPM179] to E2F4, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat
  • 免疫原

    Recombinant Human E2F4

  • 阳性对照
    • Raji cells, Tonsil.

性能

应用

Our Abpromise guarantee covers the use of ab54168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: ready to use.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein.
    • 组织特异性Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
    • 序列相似性Belongs to the E2F/DP family.
    • 发展阶段Present in the growth-arrested state, its abundance does not change significantly as cells move into and through the cell cycle.
    • 翻译后修饰Differentially phosphorylated in vivo.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • E2F 4 antibody
      • E2F transcription factor 4 antibody
      • E2F transcription factor 4 p107/p130 binding antibody
      • E2F-4 antibody
      • E2F4 antibody
      • E2F4_HUMAN antibody
      • p107/p130 binding protein antibody
      • Transcription factor E2F 4 antibody
      • Transcription factor E2F4 antibody
      see all

    Anti-E2F4 antibody [SPM179], prediluted 图像

    • immunohistochemical staining of formalin fixed, paraffin embedded human tonsil tissue section using ab54168.

    Anti-E2F4 antibody [SPM179], prediluted (ab54168)参考文献

    ab54168 has not yet been referenced specifically in any publications.

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