概述

  • 产品名称Anti-E2F2抗体
    参阅全部 E2F2 一抗
  • 描述
    兔多克隆抗体to E2F2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide:

    LFDSY

    , corresponding to a region around amino acids 425-429 of Human E2F2 (Q14209 ).

  • 阳性对照
    • HeLa and K562 extracts

性能

应用

Our Abpromise guarantee covers the use of ab123374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 45 kDa (predicted molecular weight: 48 kDa).

靶标

  • 功能Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.
  • 组织特异性Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples.
  • 序列相似性Belongs to the E2F/DP family.
  • 翻译后修饰Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • dE2F2 antibody
    • E2F transcription factor 2 antibody
    • E2F-2 antibody
    • E2F2 antibody
    • E2F2_HUMAN antibody
    • Transcription factor E2F2 antibody
    see all

Anti-E2F2 antibody 图像

  • All lanes : Anti-E2F2 antibody (ab123374) at 1/500 dilution

    Lane 1 : HeLa extract
    Lane 2 : K562 extract


    Predicted band size : 48 kDa

Anti-E2F2 antibody (ab123374)参考文献

ab123374 has not yet been referenced specifically in any publications.

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