Anti-E2F2抗体[2302C4a] (ab70731)

概述

  • 产品名称
    Anti-E2F2抗体[2302C4a]
    参阅全部 E2F2 一抗
  • 描述
    小鼠单克隆抗体[2302C4a] to E2F2
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment derived from internal sequence of human E2F2.

  • 阳性对照
    • Recombinant human E2F2.

性能

应用

Our Abpromise guarantee covers the use of ab70731 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 48 kDa.
Dot blot Use at an assay dependent dilution.

靶标

  • 功能
    Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.
  • 组织特异性
    Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples.
  • 序列相似性
    Belongs to the E2F/DP family.
  • 翻译后修饰
    Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • dE2F2 antibody
    • E2F transcription factor 2 antibody
    • E2F-2 antibody
    • E2F2 antibody
    • E2F2_HUMAN antibody
    • Transcription factor E2F2 antibody
    see all

图片

  • Anti-E2F2 antibody [2302C4a] (ab70731) + immunising recombinant protein

    Predicted band size : 48 kDa
    Observed band size : 48 kDa

实验方案

文献

ab70731 has not yet been referenced specifically in any publications.

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