Anti-E. coli heat labile toxin B抗体[BB2] (ab37203)


  • 产品名称Anti-E. coli heat labile toxin B抗体[BB2]
  • 描述
    小鼠单克隆抗体[BB2] to E. coli heat labile toxin B
  • 特异性Esherichia coli heat labile enterotoxin B chain
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Escherichia coli
  • 免疫原

    E.coli heat labile toxin, recombinant subunit B, expressed in E.coli.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯化说明Salt precipitation. Purity = 80 % (SDS-PAGE)
  • 克隆单克隆
  • 克隆编号BB2
  • 同种型IgG2b
  • 研究领域


Our Abpromise guarantee covers the use of ab37203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 14 kDa.


  • 相关性Escherichia coli heat-labile enterotoxin (LT) is the causative agent of traveller's diarrhoea, and it is also responsible for the deaths of hundreds of thousands of children per year in developing countries. LT is highly homologous in sequence, structure and function to cholera toxin (CT). Both toxins attack intestinal epithelial cells via specific binding to the branched pentasaccharide of ganglioside GM1 at the cell surface. LT is a plasmid-encoded, high molecular weight toxin, the crystalline structure of which revealed that it is composed of one A subunit (LTA) (27 kDa) and five non-covalently associated B subunits (LTB) (11.6 kDa each) forming a ring-like pentamer. The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. The B chain has a membrane binding function. A receptor-binding antagonist which blocked the interaction of LT and CT with cell suface GM1 would potentially constitute a prophylactic drug conferring protection both against the severe effects of cholera itself and against the milder but more common disease caused by LT.
  • 细胞定位Secreted
  • 数据库链接
    • 别名
      • eltB antibody
      • Heat labile enterotoxin B chain antibody
      • LTB antibody
      • LTH B antibody
      • LTP B antibody
      see all

    Anti-E. coli heat labile toxin B antibody [BB2] (ab37203)参考文献

    This product has been referenced in:
    • Becker PM  et al. Inhibition of binding of the AB5-type enterotoxins LT-I and cholera toxin to ganglioside GM1 by galactose-rich dietary components. Foodborne Pathog Dis 7:225-33 (2010). ELISA ; Escherichia coli . Read more (PubMed: 19919285) »

    See 1 Publication for this product

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    Thank you for contacting us.

    We have heaard back from the lab regarding epitope recognition of this product. Unfortunatley they have informed us that they have not mapped this epitope.

    I hope this information is helpful to you. ...

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    I am sorry for the delay in getting back to you.

    I now have further information to share with you from the lab in regards to the anti-E. coli heat labile toxin B antibody [BB12] (ab37204). The lab have retested this antibody as well as the ant...

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