Anti-Dystrophia myotonica protein kinase抗体(ab102804)


  • 产品名称
    Anti-Dystrophia myotonica protein kinase抗体
    参阅全部 Dystrophia myotonica protein kinase 一抗
  • 描述
    兔多克隆抗体to Dystrophia myotonica protein kinase
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-629 of Human Dystrophia myotonica protein kinase (NP_004400.4).

  • 阳性对照
    • HeLa cell lysate; Dystrophia myotonica protein kinase transfected 293T cell line.



Our Abpromise guarantee covers the use of ab102804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 70 kDa.


  • 功能
    Critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity. Phosphorylates phospholamban.
  • 组织特异性
    Most isoforms are expressed in many tissues including heart, skeletal muscle, liver and brain, except for isoform 2 which is only found in the heart and skeletal muscle, and isoform 14 which is only found in the brain, with high levels in the striatum, cerebellar cortex and pons.
  • 疾病相关
    Defects in DMPK are the cause of dystrophia myotonica type 1 (DM1) [MIM:160900]; also known as Steinert disease. A muscular disorder characterized by myotonia, muscle wasting in the distal extremities, cataract, hypogonadism, defective endocrine functions, male baldness and cardiac arrhythmias. Note=The causative mutation is a CTG expansion in the 3'-UTR of the DMPK gene. A length exceeding 50 CTG repeats is pathogenic, while normal individuals have 5 to 37 repeats. Intermediate alleles with 35-49 triplets are not disease-causing but show instability in intergenerational transmissions. Disease severity varies with the number of repeats: mildly affected persons have 50 to 150 repeats, patients with classic DM have 100 to 1,000 repeats, and those with congenital onset can have more than 2,000 repeats.
  • 序列相似性
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DM 1 antibody
    • DM antibody
    • DM kinase antibody
    • DM protein kinase antibody
    • DM-kinase antibody
    • DM1 antibody
    • DM1 protein kinase antibody
    • DM1PK antibody
    • DMK antibody
    • DMPK antibody
    • DMPK_HUMAN antibody
    • Dystrophia myotonica 1 antibody
    • Dystrophia myotonica protein kinase antibody
    • MDPK antibody
    • MT PK antibody
    • MT-PK antibody
    • Myotonic dystrophy associated protein kinase antibody
    • Myotonic dystrophy protein kinase antibody
    • Myotonin protein kinase A antibody
    • Myotonin protein kinase antibody
    • Myotonin-protein kinase antibody
    • Thymopoietin homolog antibody
    see all

Anti-Dystrophia myotonica protein kinase antibody 图像

  • Anti-Dystrophia myotonica protein kinase antibody (ab102804) at 1/500 dilution + HeLa cell lysate at 50 µg

    Predicted band size : 70 kDa
  • All lanes : Anti-Dystrophia myotonica protein kinase antibody (ab102804) at 1/500 dilution

    Lane 1 : Dystrophia myotonica protein kinase transfected 293T cell line
    Lane 2 : Non-transfected 293T cell line

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 70 kDa


Anti-Dystrophia myotonica protein kinase antibody (ab102804)参考文献

ab102804 has not yet been referenced specifically in any publications.

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