Anti-DYRK3抗体- N-terminal (ab72077)

概述

  • 产品名称Anti-DYRK3抗体- N-terminal
    参阅全部 DYRK3 一抗
  • 描述
    兔多克隆抗体to DYRK3 - N-terminal
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human DYRK3 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • Jurkat cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab72077 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 66 kDa (predicted molecular weight: 66 kDa).

靶标

  • 功能Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
  • 组织特异性Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
  • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated on tyrosine residues.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
    • Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
    • Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
    • Dyrk3 antibody
    • DYRK3_HUMAN antibody
    • DYRK5 antibody
    • hYAK3 2 antibody
    • Protein kinase Dyrk3 antibody
    • RED antibody
    • REDK antibody
    • Regulatory erythroid kinase antibody
    see all

Anti-DYRK3 antibody - N-terminal 图像

  • Anti-DYRK3 antibody - N-terminal (ab72077) at 1/1000 dilution + Jurkat cell lysate at 12.5 µg

    Secondary
    HRP-anti-rabbit

    Predicted band size : 66 kDa
    Observed band size : 66 kDa
    Additional bands at : 24 kDa,37 kDa,50 kDa. We are unsure as to the identity of these extra bands.

Anti-DYRK3 antibody - N-terminal (ab72077)参考文献

ab72077 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab72077.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"