概述

  • 产品名称
  • 描述
    兔多克隆抗体to DYRK3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 243 and 542 of DYRK3.

  • 阳性对照
    • Raji cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab96617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 66 kDa.

靶标

  • 功能
    Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
  • 组织特异性
    Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
  • 序列相似性
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Autophosphorylated on tyrosine residues.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
    • Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
    • Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
    • Dyrk3 antibody
    • DYRK3_HUMAN antibody
    • DYRK5 antibody
    • hYAK3 2 antibody
    • Protein kinase Dyrk3 antibody
    • RED antibody
    • REDK antibody
    • Regulatory erythroid kinase antibody
    see all

图片

  • Anti-DYRK3 antibody (ab96617) at 1/1000 dilution + Raji whole cell lyaste at 30 µg

    Predicted band size : 66 kDa

实验方案

文献

ab96617 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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