Anti-Dynein intermediate chain 2抗体(ab72746)

概述

  • 产品名称Anti-Dynein intermediate chain 2抗体
    参阅全部 Dynein intermediate chain 2 一抗
  • 描述
    小鼠多克隆抗体to Dynein intermediate chain 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human Dynein intermediate chain 2 protein (AAH39582).

  • 阳性对照
    • Dynein intermediate chain 2 transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab72746 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 69 kDa.

靶标

  • 功能Part of the dynein complex of respiratory cilia.
  • 组织特异性Highly expressed in trachea and testis.
  • 疾病相关Defects in DNAI2 are the cause of primary ciliary dyskinesia type 9 (CILD9) [MIM:612444]. CILD is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
  • 序列相似性Belongs to the dynein intermediate chain family.
    Contains 5 WD repeats.
  • 细胞定位Cytoplasm > cytoskeleton > cilium axoneme.
  • Information by UniProt
  • 数据库链接
  • 别名
    • axonemal antibody
    • Axonemal dynein intermediate chain 2 antibody
    • CILD9 antibody
    • DNAI 2 antibody
    • Dnai2 antibody
    • DNAI2_HUMAN antibody
    • Dynein axonemal intermediate chain 2 antibody
    • Dynein axonemal intermediate polypeptide 2 antibody
    • Dynein intermediate chain 2 antibody
    • Dynein intermediate chain 2 axonemal antibody
    see all

Anti-Dynein intermediate chain 2 antibody 图像

  • All lanes : Anti-Dynein intermediate chain 2 antibody (ab72746) at 1/500 dilution

    Lane 1 : Dynein intermediate chain 2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 69 kDa
    Observed band size : 69 kDa

Anti-Dynein intermediate chain 2 antibody (ab72746)参考文献

ab72746 has not yet been referenced specifically in any publications.

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