概述

  • 产品名称Anti-Dynein抗体
    参阅全部 Dynein 一抗
  • 描述
    兔多克隆抗体to Dynein
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthesized peptide derived from the N-terminal of Human Dynein.

  • 阳性对照
    • Human lung carcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111177 is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
  • 序列相似性Belongs to the dynein light chain family.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 8 kDa dynein light chain b antibody
    • C87222 antibody
    • cytoplasmic antibody
    • Dlc2 antibody
    • DLC8b antibody
    • DNCL1B antibody
    • DYL2_HUMAN antibody
    • Dynein light chain 2 antibody
    • Dynein light chain 2, cytoplasmic antibody
    • Dynein light chain LC8 type 2 antibody
    • Dynein light chain LC8-type 2 antibody
    • Dynll2 antibody
    • MGC17810 antibody
    • MGC72334 antibody
    see all

Anti-Dynein antibody 图像

  • ab111177 at 1/50 dilution, staining Dynein in paraffin-embedded Human lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-Dynein antibody (ab111177)参考文献

ab111177 has not yet been referenced specifically in any publications.

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