概述

  • 产品名称Anti-Dux4抗体
    参阅全部 Dux4 一抗
  • 描述
    兔多克隆抗体to Dux4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 253-283 of Human Dux4 (Q9UBX2).

  • 阳性对照
    • HL-60 cell line lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab110555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 45 kDa.

靶标

  • 相关性DUX4 is a homeodomain protein with a similar protein sequence to Pax3 and Pax7. Defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD). FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Severity is highly variable. Weakness is slowly progressive and about 20% of affected individuals eventually require a wheelchair. Approximately 70-90% of individuals have inherited the disease-causing deletion from a parent, and approximately 10-30% of affected individuals have FSHD as the result of a de novo deletion. Offsprings of an affected individual have a 50% chance of inheriting the deletion.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • Double homeobox protein 10 antibody
    • Double homeobox protein 4 antibody
    • Double homeobox protein 4/10 antibody
    • DUX10 antibody
    • DUX4L1 antibody
    see all

Anti-Dux4 antibody 图像

  • Anti-Dux4 antibody (ab110555) at 1/100 dilution + HL-60 cell line lysate at 35 µg

    Predicted band size : 45 kDa

Anti-Dux4 antibody (ab110555)参考文献

ab110555 has not yet been referenced specifically in any publications.

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