概述

  • 产品名称Anti-DUT抗体
    参阅全部 DUT 一抗
  • 描述
    小鼠单克隆抗体to DUT
  • 经测试应用适用于: IHC-P, WB, ICC/IFmore details
  • 种属反应性
    与反应: Human, Recombinant Fragment
  • 免疫原

    Recombinant fragment: TDIQIALPSG CYGRVAPRSG LAAKHFIDVG AGVIDEDYRG NVGVVLFNFG KEKFEVKKGD RIAQLICERI FYPEIEEVQA LDDTERGSGG FGSTGKN, corresponding to amino acids 68-164 of Human DUT-N

性能

应用

Our Abpromise guarantee covers the use of ab54942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
ICC/IF
  • 应用说明ICC/IF: Use at a concentration of 10 µg/ml.
    IHC-P: Use at a concentration of 1 µg/ml.
    WB: Use at a concentration of 1 - 5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    • 组织特异性Found in a variety of tissues.
    • 通路Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.
    • 序列相似性Belongs to the dUTPase family.
    • 翻译后修饰Phosphorylation in mature T-cells occur in a cell cycle-dependent manner.
    • 细胞定位Mitochondrion and Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Deoxyuridine 5' triphosphate nucleotidohydrolase, nuclear isoform antibody
      • Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial antibody
      • Deoxyuridine triphosphatase antibody
      • dut antibody
      • DUT_HUMAN antibody
      • dUTP nucleotidohydrolase antibody
      • dUTP pyrophosphatase antibody
      • dUTPase antibody
      • FLJ20622 antibody
      see all

    Anti-DUT antibody 图像

    • DUT-N antibody (ab54942) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human colon.
    • Western blot against tagged recombinant protein immunogen using ab54942 DUT-N antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa
    • ab54942 at 10 ug/ml staining DUT-N in human Hela cells by Immunocytochemistry / Immunofluorescence.

    Anti-DUT antibody (ab54942)参考文献

    ab54942 has not yet been referenced specifically in any publications.

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