Anti-DUSP10抗体(ab2272)

概述

  • 产品名称Anti-DUSP10抗体
    参阅全部 DUSP10 一抗
  • 描述
    山羊多克隆抗体to DUSP10
  • 特异性This antibody is expected to recognise isoform a (NP_009138.1) and isoform b (NP_653329.1 and NP_653330.1).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide: RILTPKLMGVETVV, corresponding to C terminal amino acids 469-482 of Human DUSP10.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab2272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Can be blocked with Human DUSP10 peptide (ab22899).

靶标

  • 功能Involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.
  • 序列相似性Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Dual specificity phosphatase 10 antibody
    • Dual specificity phosphatase MKP 5 antibody
    • Dual specificity phosphatase MKP5 antibody
    • Dual specificity protein phosphatase 10 antibody
    • DUS10_HUMAN antibody
    • DUSP 10 antibody
    • DUSP10 antibody
    • DUSP10 protein antibody
    • MAP kinase phosphatase 5 antibody
    • Mitogen activated protein kinase phosphatase 5 antibody
    • Mitogen-activated protein kinase phosphatase 5 antibody
    • MKP 5 antibody
    • MKP-5 antibody
    • MKP5 antibody
    • Serine/threonine specific protein phosphatase antibody
    see all

Anti-DUSP10 antibody 图像

  • ab2272 staining (0.5µg/ml) of Human Liver lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-DUSP10 antibody (ab2272)参考文献

ab2272 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. This product had been tested on adult human liver lysate, made in RIPA buffer (1% TritonX100 instead of NP40). However, the product has not been tested on HepG2 or Huh-7, but I would expect similar results in HepG2. I ...

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There are 3 different sequences of Dusp10 listed in the reviewed locuslink entry(http://www.ncbi.nlm.nih.gov/LocusLink/LocRpt.cgi?l=11221). Our peptide sequence is found in all three, however we never saw the smaller isoforms in WB. For that reason...

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Thank you for your enquiry. We do not routinely offer free or trial sized samples for testing purposes. Our policy at Abcam is that if an antibody does not work as specified on the datasheet, we will offer a replacement or reimbursement. Should you dec...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"