Anti-DUSP1抗体(ab37493)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to DUSP1
  • 特异性
    Targets N terminus of DUSP1.
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids within residues 1-100 of DUSP1 (Human)

  • 阳性对照
    • HEK 293 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab37493 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).

靶标

  • 功能
    Dual specificity phosphatase that dephosphorylates MAP kinase ERK2 on both 'Thr-183' and 'Tyr-185'.
  • 组织特异性
    Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
  • 序列相似性
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CL 100 antibody
    • CL100 antibody
    • Dual Specificity Phosphatase 1 antibody
    • Dual specificity protein phosphatase 1 antibody
    • Dual specificity protein phosphatase hVH1 antibody
    • DUS1_HUMAN antibody
    • DUSP 1 antibody
    • Dusp1 antibody
    • HVH1 antibody
    • MAP kinase phosphatase 1 antibody
    • Mitogen-activated protein kinase phosphatase 1 antibody
    • MKP-1 antibody
    • MKP1 antibody
    • Protein tyrosine phosphatase CL100 antibody
    • Protein-tyrosine phosphatase CL100 antibody
    • PTPN10 antibody
    • Serine/threonine specific protein phosphatase antibody
    • VH1 antibody
    see all

图片

  • Anti-DUSP1 antibody (ab37493) + HEK 293 cell lysate.

    Predicted band size : 39 kDa
    Observed band size : 39 kDa
    Additional bands at : 16 kDa,22 kDa,75 kDa. We are unsure as to the identity of these extra bands.

实验方案

文献

ab37493 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your enquiry. The optimal conditions for this antibody fall within these guidelines: 1) At an antibody concentration of 2ug/ml, the amount of protein loaded should be ~10ug 2. The blocking reagent: 3% milk in TBST 3. The...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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