概述

  • 产品名称
  • 描述
    山羊多克隆抗体to DTX3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Cow, Human
  • 免疫原

    Synthetic peptide:

    KNKVTVSKPVWD

    by a Cysteine residue linker, corresponding to internal sequence amino acids 16-27 of Mouse DTX3 (NP_848597.1)

  • 阳性对照
    • NIH3T3 lysate, Mouse Fetal Brain lysate

性能

应用

Our Abpromise guarantee covers the use of ab99092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 0.5 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 38 kDa). The observed much higher molecular weight corresponds to earlier findings in literature with different antibodies.

靶标

  • 功能
    Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
  • 序列相似性
    Belongs to the Deltex family.
    Contains 1 RING-type zinc finger.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Deltex3 antibody
    • Dtx3 antibody
    • DTX3_HUMAN antibody
    • Protein deltex 3 antibody
    • Protein deltex-3 antibody
    • RING finger protein 154 antibody
    • RNF154 antibody
    see all

图片

  • Anti-DTX3 antibody (ab99092) at 0.3 µg/ml (incubated for 1 hour) + NIH3T3 cell lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 38 kDa

实验方案

文献

ab99092 has not yet been referenced specifically in any publications.

客户评价及客户问答

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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