概述

  • 产品名称Anti-DTX2抗体
    参阅全部 DTX2 一抗
  • 描述
    兔多克隆抗体to DTX2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 454-503 (EDCGTILIVY SIPHGIQGPE HPNPGKPFTA RGFPRQCYLP DNAQGRKVLE) of Human DTX2(NP_001096066).

  • 阳性对照
    • HepG2 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab106332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 62 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the Deltex family.
    Contains 1 RING-type zinc finger.
    Contains 2 WWE domains.
  • 结构域The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases.
  • 细胞定位Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Deltex 2 antibody
    • deltex homolog 2 (Drosophila) antibody
    • deltex, Drosophila, homolog of, 2 antibody
    • Deltex2 antibody
    • DTX2 antibody
    • DTX2_HUMAN antibody
    • hDTX2 antibody
    • Highly similar to hPMSR6 [H.sapiens] antibody
    • KIAA1528 antibody
    • Probable E3 ubiquitin-protein ligase DTX2 antibody
    • Protein deltex 2 antibody
    • Protein deltex-2 antibody
    • RING finger protein 58 antibody
    • RNF58 antibody
    • Zinc ion binding protein antibody
    see all

Anti-DTX2 antibody 图像

  • Anti-DTX2 antibody (ab106332) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 62 kDa

Anti-DTX2 antibody (ab106332)参考文献

ab106332 has not yet been referenced specifically in any publications.

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