概述

  • 产品名称Anti-DRG2抗体
    参阅全部 DRG2 一抗
  • 描述
    兔多克隆抗体to DRG2
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen, corresponding to amino acids 210-359 of Human DRG2 (P55039).

  • 阳性对照
    • Human kidney tissue, Human cell line U-2 OS

性能

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应用

Our Abpromise guarantee covers the use of ab121268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6, using a pressure boiler
ICC/IF Use a concentration of 1 - 4 µg/ml. The following steps are recommended prior to antibody incubation: cells fixation in ice cold 4% paraformaldehyde pH 7.2-7.3, followed by permeabilization with 0.1% Triton X-100 in PBS for 3x5 minutes.

靶标

  • 功能May play a role in cell proliferation, differentiation and death.
  • 组织特异性Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.
  • 序列相似性Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • 翻译后修饰Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Developmentally regulated GTP binding protein 2 antibody
    • Developmentally-regulated GTP-binding protein 2 antibody
    • DRG 2 antibody
    • DRG-2 antibody
    • drg2 antibody
    • DRG2_HUMAN antibody
    see all

Anti-DRG2 antibody 图像

  • ab121268 at 1/35 dilution staining DRG2 in Human kidney by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
  • ab121268 at 4 µg/ml staining DRG2 in Human cell line U-2 OS by Immunofluorescent staining. Antibody staining is shown in green.

Anti-DRG2 antibody (ab121268)参考文献

ab121268 has not yet been referenced specifically in any publications.

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