概述

  • 产品名称
    Anti-DRAM2抗体
  • 描述
    兔多克隆抗体to DRAM2
  • 经测试应用
    适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: ISLRVEANLH GLTLYDTAPC PINNERTRLL SRDI, corresponding to C terminal amino acids 233-266 of Human DRAM2.

  • 阳性对照
    • Human small intestine tissue; Human U 2 OS cells.

性能

应用

Our Abpromise guarantee covers the use of ab121554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Recommended fixation/permeabilization: PFA/Triton X-100

靶标

  • 功能
    Induces apoptotic cell death when co-expressed with DRAM1.
  • 组织特异性
    Expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Not detected in brain or thymus.
  • 序列相似性
    Belongs to the DRAM/TMEM150 family.
  • 细胞定位
    Lysosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2010305N14Rik antibody
    • 2610318G18Rik antibody
    • AI647667 antibody
    • damage regulated autophagy modulator 2 antibody
    • DNA damage regulated autophagy modulator 2 antibody
    • DNA damage regulated autophagy modulator protein 2 antibody
    • DNA damage-regulated autophagy modulator protein 2 antibody
    • Dram2 antibody
    • DRAM2_HUMAN antibody
    • PRO180 antibody
    • PSEC0031 antibody
    • RP5-1180E21.1 antibody
    • Tmem77 antibody
    • Transmembrane protein 77 antibody
    • WWFQ154 antibody
    see all

图片

  • ab121554 at 1/100 dilution staining DRAM2 in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.
    Note: granular cytoplasmic positivity in glandular cells.
  • ab121554 at 4 µg/ml staining DRAM2 in PFA/Triton X-100 fixed/permeabilized U2 OS cells by Immunofluorescence (green).
    Note: positivity in golgi apparatus & vesicles.

文献

ab121554 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab121554.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册