Anti-DRAM2抗体(ab121554)
Key features and details
- Rabbit polyclonal to DRAM2
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-DRAM2抗体 -
描述
兔多克隆抗体to DRAM2 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence: ISLRVEANLH GLTLYDTAPC PINNERTRLL SRDI, corresponding to C terminal amino acids 233-266 of Human DRAM2.
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阳性对照
- Human small intestine tissue; Human U 2 OS cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121554于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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说明 |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
靶标
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功能
Induces apoptotic cell death when co-expressed with DRAM1. -
组织特异性
Expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Not detected in brain or thymus. -
序列相似性
Belongs to the DRAM/TMEM150 family. -
细胞定位
Lysosome membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 128338 Human
- Omim: 613360 Human
- SwissProt: Q6UX65 Human
- Unigene: 485606 Human
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别名
- 2010305N14Rik antibody
- 2610318G18Rik antibody
- AI647667 antibody
see all
图片
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ab121554 at 1/100 dilution staining DRAM2 in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.
Note: granular cytoplasmic positivity in glandular cells. -
ab121554 at 4 µg/ml staining DRAM2 in PFA/Triton X-100 fixed/permeabilized U2 OS cells by Immunofluorescence (green).
Note: positivity in golgi apparatus & vesicles.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab121554 尚未被引用在任何文献中。