概述

  • 产品名称Anti-DRAK1抗体
    参阅全部 DRAK1 一抗
  • 描述
    兔多克隆抗体to DRAK1
  • 特异性No reactivity to DRAK2, DAP or ZIP kinases.
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    EKPGSGGSSPGATSGC

    , corresponding to amino acids 5-19 of Human DRAK1. (Peptide available as ab8453.)

  • 阳性对照
    • A431 or MOLT4 whole cell lysate An approximately 50 kDa band can be detected.

性能

应用

Our Abpromise guarantee covers the use of ab8418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa.Can be blocked with Human DRAK1 peptide (ab8453).
ICC/IF Use a concentration of 2 µg/ml.

靶标

  • 功能Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.
  • 组织特异性Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DAP kinase-related apoptosis-inducing protein kinase 1 antibody
    • death-associated protein kinase-related 1 antibody
    • DRAK1 antibody
    • EC 2.7.11.1 antibody
    • Serine / threonine kinase 17a death associated protein kinase related 1 antibody
    • Serine/threonine kinase 17a antibody
    • Serine/threonine protein kinase 17a antibody
    • Serine/threonine-protein kinase 17A antibody
    • ST17A_HUMAN antibody
    • STK17 A antibody
    • STK17A antibody
    see all

Anti-DRAK1 antibody 图像

  • All lanes : Anti-DRAK1 antibody (ab8418) at 1/500 dilution

    Lane 1 : MOLT4 whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : 3T3 whole cell lysate


    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
  • ab8418 at 2µg/ml staining DRAK1 in MOLT4 cells by ICC/IF

Anti-DRAK1 antibody (ab8418)参考文献

ab8418 has not yet been referenced specifically in any publications.

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