Anti-DR5抗体[MD5-1] (Phycoerythrin) (ab95619)


  • 产品名称Anti-DR5抗体[MD5-1] (Phycoerythrin)
    参阅全部 DR5 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[MD5-1] to DR5 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse DR5.

  • 阳性对照
    • Mouse DR5 transfected BHK cells.



Our Abpromise guarantee covers the use of ab95619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.125-0.25µg for 105-8 cells. Staining the cell sample in a final volume of 100 µl is recommended.

ab101026-Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.


  • 功能Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
  • 组织特异性Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain.
  • 疾病相关Squamous cell carcinoma of the head and neck
  • 序列相似性Contains 1 death domain.
    Contains 3 TNFR-Cys repeats.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Fas like protein antibody
    • Apoptosis inducing protein TRICK2A/2B antibody
    • Apoptosis inducing receptor TRAIL R2 antibody
    • CD262 antibody
    • CD262 antigen antibody
    • Cytotoxic TRAIL receptor 2 antibody
    • Death domain containing receptor for TRAIL/Apo 2L antibody
    • Death receptor 5 antibody
    • DR5 antibody
    • KILLER antibody
    • KILLER/DR5 antibody
    • OTTHUMP00000123492 antibody
    • OTTHUMP00000123493 antibody
    • p53 regulated DNA damage inducible cell death receptor(killer) antibody
    • TNF related apoptosis inducing ligand receptor 2 antibody
    • TNF-related apoptosis-inducing ligand receptor 2 antibody
    • TNFRSF10B antibody
    • TR10B_HUMAN antibody
    • TRAIL R2 antibody
    • TRAIL receptor 2 antibody
    • TRAIL-R2 antibody
    • TRAILR2 antibody
    • TRICK2 antibody
    • TRICK2A antibody
    • TRICK2B antibody
    • TRICKB antibody
    • Tumor necrosis factor receptor like protein ZTNFR9 antibody
    • Tumor necrosis factor receptor superfamily member 10B antibody
    • Tumor necrosis factor receptor superfamily, member 10b antibody
    • ZTNFR9 antibody
    see all

Anti-DR5 antibody [MD5-1] (Phycoerythrin) 图像

  • Flow cytometry staining of non-transfected (left) and mouse DR5 transfected (right) BHK cells with 0.125 µg of Golden Syrian Hamster IgG Isotype Control PE (open histogram) or 0.125 µg of ab95619 (filled histogram). Total viable cells were used for analysis.

Anti-DR5 antibody [MD5-1] (Phycoerythrin) (ab95619)参考文献

ab95619 has not yet been referenced specifically in any publications.

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