Mouse, Rat, Human
, corresponding to extracellular amino acids 59-77 of Human DR3
(Peptide available as ab8444
- Jurkat total cell lysate
A 59 kDa band should be detected.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/1000. Detects a band of approximately 59 kDa.Can be blocked with Human DR3 peptide (ab8444).
||Use a concentration of 10 µg/ml.
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
Contains 1 death domain.
Contains 4 TNFR-Cys repeats.
Secreted and Cell membrane.
Information by UniProt
- Apo 3 antibody
- Apo-3 antibody
- Apo3 antibody
Anti-DR3 antibody 图像
Western blot - DR3 antibody (ab8412)
Immunocytochemistry/ Immunofluorescence - DR3 antibody (ab8412)
ab8412 at 10µg/ml staining DR3 in Jurkat cells by ICC/IF
Anti-DR3 antibody (ab8412)参考文献
has not yet been referenced specifically in any publications.
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