Anti-DR1抗体- ChIP Grade (ab50783)

概述

• 产品名称Anti-DR1抗体- ChIP Grade
  参阅全部 DR1 一抗
• 描述
  兔多克隆抗体to DR1 - ChIP Grade
• 经测试应用适用于: WB, ChIP, ELISAmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse, Rat, Cow, Dog, Zebrafish
• 免疫原

  A region within synthetic peptide: MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI, corresponding to N terminal amino acids 1-50 of Human DR1

  Run BLAST with Run BLAST with
• 阳性对照
  • Transfected 293T Cell Lysate

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• 存储溶液Constituents: 2% Sucrose, PBS
• Concentration information loading...
• 纯度Protein A purified
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Polymerase associated factors
  • Pol II Transcription
  • Other

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Other factors

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Transcription Factors

  • Epigenetics and Nuclear Signaling
  • ChIP'ing antibodies
  • ChIP'ing antibodies

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 功能The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
• 序列相似性Belongs to the NC2 beta/DR1 family.
  Contains 1 histone-fold domain.
• 翻译后修饰Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.
• 细胞定位Nucleus.

• Target information above from: UniProt accession Q01658 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 1810 Human
  • Entrez Gene: 13486 Mouse
  • Entrez Gene: 289881 Rat
  • Omim: 601482 Human
  • SwissProt: Q01658 Human
  • SwissProt: Q91WV0 Mouse
  • SwissProt: Q5XI68 Rat
  • Unigene: 348418 Human

  • Unigene: 303534 Mouse
  • Unigene: 6666 Rat

  see all
• 别名
  • Down regulator of transcription 1 antibody
  • Down regulator of transcription 1 TBP binding antibody
  • Down-regulator of transcription 1 antibody

  • down-regulator of transcription 1, TBP-binding (negative cofactor 2) antibody
  • DR 1 antibody
  • Dr1 antibody
  • Dr1 protein antibody
  • NC 2 antibody
  • NC2 antibody
  • NC2 beta antibody
  • NC2-beta antibody
  • NC2B_HUMAN antibody
  • Negative co factor 2 antibody
  • Negative cofactor 2 antibody
  • Negative cofactor 2 beta antibody
  • Negative cofactor 2-beta antibody
  • Protein Dr1 antibody
  • TATA binding protein associated phosphoprotein antibody
  • TATA box/binding protein associated phosphoprotein DR1 antibody
  • TATA-binding protein-associated phosphoprotein antibody

  see all