概述

  • 产品名称Anti-DPY19L2抗体
  • 描述
    兔多克隆抗体to DPY19L2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide derived from within residues: IGEFNNLPQE ELLQWIKYST TSDAVFAGAM PTMASIKLST LHPIVNHPHY, corresponding to amino acids 612 - 661 of Human DPY19L2 (NP_776173)

  • 阳性对照
    • Fetal heart lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab87596 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 87 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Required during spermatogenesis for sperm head elongation and acrosome formation.
  • 组织特异性Widely expressed with high expression in testis. Not detectable in ejaculated sperm (at protein level).
  • 疾病相关Defects in DPY19L2 are a cause of globozoospermia (GLOBZOOS) [MIM:102530]. An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome. In the most severe cases the acrosome is totally absent. Globozoospermia is also characterized by abnormal nuclear shape as well as abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of GLOBZOOS.
  • 序列相似性Belongs to the dpy-19 family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • D19L2_HUMAN antibody
    • dpy 19 like 2 antibody
    • dpy 19 like 2 (C. elegans) antibody
    • Dpy 19 like protein 2 antibody
    • Dpy-19-like protein 2 antibody
    • dpy19 antibody
    • DPY19L2 antibody
    • FLJ32949 antibody
    • FLJ36166 antibody
    • Protein dpy 19 homolog 2 antibody
    • Protein dpy-19 homolog 2 antibody
    see all

Anti-DPY19L2 antibody 图像

  • Anti-DPY19L2 antibody (ab87596) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 87 kDa

Anti-DPY19L2 antibody (ab87596)参考文献

ab87596 has not yet been referenced specifically in any publications.

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