Anti-DPP6抗体- Catalytic domain (ab41811)
Key features and details
- Rabbit polyclonal to DPP6 - Catalytic domain
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-DPP6抗体- Catalytic domain
参阅全部 DPP6 一抗 -
描述
兔多克隆抗体to DPP6 - Catalytic domain -
宿主
Rabbit -
特异性
This antibody will recognize the three longest forms of DPP6 but not the 353 amino acid form. It will not recognize the other family members. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Synthetic peptide based on the catalytic domain of human DPP6.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 50% Glycerol -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab41811于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (1) |
说明 |
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靶标
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功能
Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437, PubMed:19441798). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:18364354). Has no dipeptidyl aminopeptidase activity (PubMed:8103397, PubMed:15476821). -
组织特异性
Expressed predominantly in brain. -
疾病相关
Familial paroxysmal ventricular fibrillation 2
Mental retardation, autosomal dominant 33 -
序列相似性
Belongs to the peptidase S9B family. -
翻译后修饰
N-glycosylated. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1804 Human
- Entrez Gene: 13483 Mouse
- Omim: 126141 Human
- SwissProt: P42658 Human
- SwissProt: Q9Z218 Mouse
- Unigene: 490684 Human
- Unigene: 551097 Human
- Unigene: 669076 Human
see all -
别名
- Dipeptidyl aminopeptidase IV related protein antibody
- Dipeptidyl aminopeptidase like protein 6 antibody
- Dipeptidyl aminopeptidase related protein antibody
see all
图片
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All lanes : Anti-DPP6 antibody - Catalytic domain (ab41811) at 1/1000 dilution
Lane 1 : Mouse Brain
Lane 2 : DU145 / IL1-beta Cell media
Predicted band size: 98 kDa
Observed band size: 105 kDa why is the actual band size different from the predicted?
Additional bands at: 60 kDa (possible truncated form)
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab41811 被引用在 6 文献中.
- Tabor GT et al. A novel bungarotoxin binding site-tagged construct reveals MAPK-dependent Kv4.2 trafficking. Mol Cell Neurosci 98:121-130 (2019). PubMed: 31212013
- Lin L et al. DPP6 domains responsible for its localization and function. J Biol Chem 289:32153-65 (2014). WB, IP . PubMed: 25190807
- Nadin BM & Pfaffinger PJ A new TASK for Dipeptidyl Peptidase-like Protein 6. PLoS One 8:e60831 (2013). WB ; Rat . PubMed: 23593319
- Lin L et al. DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development. Nat Commun 4:2270 (2013). PubMed: 23912628
- Nadin BM & Pfaffinger PJ Dipeptidyl peptidase-like protein 6 is required for normal electrophysiological properties of cerebellar granule cells. J Neurosci 30:8551-65 (2010). PubMed: 20573902
- Jerng HH & Pfaffinger PJ Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating. J Biol Chem 283:36046-59 (2008). WB ; Human . PubMed: 18957440