概述

  • 产品名称Anti-DPP6抗体
    参阅全部 DPP6 一抗
  • 描述
    兔多克隆抗体to DPP6
  • 特异性This antibody will recognise all four forms of DPP6, but not the other family members.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide based on the stalk region of human DPP6.

    (Peptide available as ab44766.)

性能

应用

Our Abpromise guarantee covers the use of ab41809 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/1000 when using colorimetric substrates such as BCIP/NBT, and 1/5000 for chemiluminescent substrates. Predicted molecular weight: 98 kDa. EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性DPP6 (DPPX, also known as potassium channel accelerating factor Dppx) is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.
    • 细胞定位Cell Membrane; single-pass type II membrane protein
    • 数据库链接
    • 别名
      • Dipeptidyl aminopeptidase IV related protein antibody
      • Dipeptidyl aminopeptidase like protein 6 antibody
      • Dipeptidyl aminopeptidase related protein antibody
      • Dipeptidyl peptidase 6 antibody
      • Dipeptidyl peptidase IV like protein antibody
      • Dipeptidyl peptidase IV related protein antibody
      • Dipeptidylpeptidase 6 antibody
      • Dipeptidylpeptidase VI antibody
      • DPP VI antibody
      • DPPX antibody
      • VF2 antibody
      see all

    Anti-DPP6 antibody 图像

    • All lanes : Anti-DPP6 antibody (ab41809) at 1/1000 dilution

      Lane 1 : ESB
      Lane 2 : Mouse Brain
      Lane 3 : DU145 / IL1-beta Lysate
      Lane 4 : DU145 / IL1-beta CM


      Predicted band size : 98 kDa
      Observed band size : 98 kDa
      Additional bands at : 47 kDa (possible truncated form).

    Anti-DPP6 antibody (ab41809)参考文献

    This product has been referenced in:
    • Sheikh MA  et al. Epigenetic regulation of Dpp6 expression by Dnmt3b and its novel role in the inhibition of RA induced neuronal differentiation of P19 cells. PLoS One 8:e55826 (2013). WB ; Mouse . Read more (PubMed: 23409053) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"