概述

  • 产品名称Anti-DPP2抗体
    参阅全部 DPP2 一抗
  • 描述
    兔多克隆抗体to DPP2
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human DPP2 (extracellular) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • Stomach

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.7
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab61824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 相关性DPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain (DPP-II-M), and a soluble form (DPP-II-S). First discovered as an enzyme involved in the terminal steps of protein degradation, and later as an enzyme involved in cell growth and quiescence, DPP2 cleaves N-terminal dipeptides and tripeptides from proteins. DPP2 has a preference for proline in the P1 position, and processes the tripeptides generated by DPP1 (which is unable to cleave if proline is in the P1 position). Some tumor cell lines express elevated DPP2 levels, and serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients.
  • 细胞定位Lysosome. Cytoplasmic vesicle. Secreted.
  • 数据库链接
  • 别名
    • Dipeptidyl aminopeptidase II antibody
    • Dipeptidyl peptidase 7 antibody
    • Dipeptidyl peptidase II antibody
    • DPP II antibody
    • DPP2 antibody
    • DPP7 antibody
    • DPPII antibody
    • QPP antibody
    • Quiescent cell proline dipeptidase antibody
    • Weakly similar to LYSOSOMAL PRO X CARBOXYPEPTIDASE antibody
    see all

Anti-DPP2 antibody 图像

  • ab61824, at 10µg/ml, staining human DPP2 in stomach tissue by immunohistochemistry. Formalin-fixed paraffin-embedded tissue.

Anti-DPP2 antibody (ab61824)参考文献

ab61824 has not yet been referenced specifically in any publications.

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