概述
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产品名称Anti-DPP10抗体
参阅全部 DPP10 一抗 -
描述山羊多克隆抗体to DPP10
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宿主Goat
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特异性ab31292 recognises Dipeptidylpeptidase 10.
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经测试应用适用于: WB, ELISAmore details
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种属反应性与反应: Human
预测可用于: Chicken, Cow, Dog, Chimpanzee
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免疫原
Synthetic peptide:
C-DEGHNVSEKSKYHL
, corresponding to Internal sequence amino acids 765-779 of Human DPP10 -
阳性对照
- Human Bone Marrow lysate
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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存储溶液Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline. pH 7.3 -
Concentration information loading... -
纯度Immunogen affinity purified
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纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab31292 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa). | |
| ELISA | 1/32000. |
靶标
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功能Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2.
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组织特异性Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands.
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疾病相关Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
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序列相似性Belongs to the peptidase S9B family. DPPIV subfamily.
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翻译后修饰N-glycosylated.
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细胞定位Membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 617222 Cow
- Entrez Gene: 476121 Dog
- Entrez Gene: 57628 Human
- Omim: 608209 Human
- SwissProt: Q8N608 Human
- Unigene: 580539 Human
- Unigene: 591555 Human
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别名
- Dipeptidyl peptidase 10 antibody
- Dipeptidyl peptidase 10 non functional antibody
- Dipeptidyl peptidase IV related protein 3 antibody
see all
图片
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Western blot - Anti-DPP10 antibody (ab31292)Anti-DPP10 antibody (ab31292) at 0.1 µg/ml (incubation time: 1 hour) + Human Bone Marrow lysate (35µg protein in RIPA buffer)
Developed using the ECL technique.
Predicted band size: 90 kDa
Observed band size: 90 kDa
文献
ab31292 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"