This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

概述

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab87617 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

  • 应用说明WB: This antibody did not give bands in initial tests on lysate/cell line. We would welcome your feedback if you have tested this antibody in more suitable positive controls.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性DPM2 regulates the biosynthesis of dolichol phosphate-mannose. Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by DPM2 is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.
    • 细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein.
    • 数据库链接
    • 别名
      • Dolichol phosphate (beta D) mannosyltransferase 2 antibody
      • Dolichol phosphate mannose biosynthesis regulatory protein antibody
      • Dolichol phosphate mannose synthase 2 antibody
      • Dolichyl phosphate mannosyltransferase 2 antibody
      • Dolichyl phosphate mannosyltransferase polypeptide 2, regulatory subunit antibody
      • R75484 antibody
      • RP23 255P20.5 antibody
      see all

    Anti-DPM2 antibody (ab87617)参考文献

    ab87617 has not yet been referenced specifically in any publications.

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