Anti-DP2抗体[TFD5I455] (ab50882)

概述

  • 产品名称Anti-DP2抗体[TFD5I455]
    参阅全部 DP2 一抗
  • 描述
    小鼠单克隆抗体[TFD5I455] to DP2
  • 经测试应用适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment (Human)

性能

应用

Our Abpromise guarantee covers the use of ab50882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 49 kDa.
Dot blot Use at an assay dependent dilution.

靶标

  • 功能Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
  • 组织特异性High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
  • 序列相似性Belongs to the E2F/DP family.
  • 翻译后修饰Ser-24 is probably phosphorylated by CDK2.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DP2 antibody
    • E2F dimerization partner 2 antibody
    • Tfdp2 antibody
    • TFDP2_HUMAN antibody
    • Transcription factor Dp 2 antibody
    • Transcription factor Dp-2 antibody
    see all

Anti-DP2 antibody [TFD5I455] 图像

Anti-DP2 antibody [TFD5I455] (ab50882)参考文献

ab50882 has not yet been referenced specifically in any publications.

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