Anti-DP1抗体[SPM178], prediluted (ab53924)

概述

  • 产品名称Anti-DP1抗体[SPM178], prediluted
    参阅全部 DP1 一抗
  • 描述
    小鼠单克隆抗体[SPM178] to DP1, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant DP1 protein.

  • 表位Amino acids 83-204.
  • 阳性对照
    • MAD109 or Raji cells. Human tonsil.

性能

应用

Our Abpromise guarantee covers the use of ab53924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready to use for 30 min at room temperature.
    Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
    • 组织特异性Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
    • 序列相似性Belongs to the E2F/DP family.
    • 翻译后修饰Phosphorylation by E2F-1-bound cyclin A-CDK2, in the S phase, inhibits E2F-mediated DNA binding and transactivation.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DP 1 antibody
      • DP1 antibody
      • DRTF1 antibody
      • DRTF1-polypeptide 1 antibody
      • E2F dimerization partner 1 antibody
      • E2F related transcription factor antibody
      • TFDP1 antibody
      • TFDP1_HUMAN antibody
      • Transcription factor Dp-1 antibody
      • Transcription factor sequence-specific, DRTF1 antibody
      see all

    Anti-DP1 antibody [SPM178], prediluted 图像

    • ab53924 (prediluted) staining DP1 in formalin fixed, paraffin embedded human tonsil tissue by Immunohistochemistry.

    Anti-DP1 antibody [SPM178], prediluted (ab53924)参考文献

    ab53924 has not yet been referenced specifically in any publications.

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