概述

  • 产品名称Anti-DP1抗体
    参阅全部 DP1 一抗
  • 描述
    兔多克隆抗体to DP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 360-409 (SASDLTNGAD GMLATSSNGS QYSGSRVETP VSYVGEDDEE DDDFNENDED) of Human DP1 (NP_009042).

  • 阳性对照
    • Human fetal spleen lysate

性能

应用

Our Abpromise guarantee covers the use of ab90309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
  • 组织特异性Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
  • 序列相似性Belongs to the E2F/DP family.
  • 翻译后修饰Phosphorylation by E2F-1-bound cyclin A-CDK2, in the S phase, inhibits E2F-mediated DNA binding and transactivation.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DP 1 antibody
    • DP1 antibody
    • DRTF1 antibody
    • DRTF1-polypeptide 1 antibody
    • E2F dimerization partner 1 antibody
    • E2F related transcription factor antibody
    • TFDP1 antibody
    • TFDP1_HUMAN antibody
    • Transcription factor Dp-1 antibody
    • Transcription factor sequence-specific, DRTF1 antibody
    see all

Anti-DP1 antibody 图像

  • Anti-DP1 antibody (ab90309) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

    Secondary
    HRP conjugated anti-rabbit IgG at 1/50000 dilution

    Predicted band size : 45 kDa

Anti-DP1 antibody (ab90309)参考文献

ab90309 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab90309.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"