Anti-Dopamine Receptor D5抗体, prediluted (ab32621)

概述

  • 产品名称Anti-Dopamine Receptor D5抗体, prediluted
    参阅全部 Dopamine Receptor D5 一抗
  • 描述
    兔多克隆抗体to Dopamine Receptor D5, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chicken
  • 免疫原

    Synthetic peptide:

    CEGEISLDKI TPFTPNGFH

    , corresponding to C terminal amino acids 459-477 of Human Dopamine Receptor D5.

  • 阳性对照
    • Human brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab32621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Use Neat for 30 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
    • 组织特异性Neuron-specific, localized primarily within limbic regions of the brain.
    • 疾病相关Defects in DRD5 are a cause of benign essential blepharospasm (BEB) [MIM:606798]. BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
    • 序列相似性Belongs to the G-protein coupled receptor 1 family.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • D(1B) dopamine receptor antibody
      • D(5) dopamine receptor antibody
      • D1 beta dopamine receptor antibody
      • D1B dopamine receptor antibody
      • D1beta dopamine receptor antibody
      • D5 dopamine receptor antibody
      • DBDR antibody
      • Dopamine D5 receptor antibody
      • Dopamine receptor D1B antibody
      • dopamine receptor D5 antibody
      • DRD 1B antibody
      • DRD 5 antibody
      • DRD1B antibody
      • DRD1L2 antibody
      • DRD5 antibody
      • DRD5_HUMAN antibody
      • MGC10601 antibody
      see all

    Anti-Dopamine Receptor D5 antibody, prediluted 图像

    • Ab32621, prediluted, staining Dopamine Receptor D5 in formalin fixed paraffin embedded human brain tissue sections by Immunohistochemistry.

    Anti-Dopamine Receptor D5 antibody, prediluted (ab32621)参考文献

    ab32621 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab32621.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"