Anti-Dopamine Receptor D5抗体(ab32620)


  • 产品名称Anti-Dopamine Receptor D5抗体
    参阅全部 Dopamine Receptor D5 一抗
  • 描述
    兔多克隆抗体to Dopamine Receptor D5
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chicken
  • 免疫原

    Synthetic peptide: CEGEISLDKI TPFTPNGFH, corresponding to C terminal amino acids 459-477 of Human Dopamine Receptor D5.

  • 阳性对照
    • Human brain tissue.



Our Abpromise guarantee covers the use of ab32620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF Use a concentration of 5 µg/ml.


  • 功能Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
  • 组织特异性Neuron-specific, localized primarily within limbic regions of the brain.
  • 疾病相关Defects in DRD5 are a cause of benign essential blepharospasm (BEB) [MIM:606798]. BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • D(1B) dopamine receptor antibody
    • D(5) dopamine receptor antibody
    • D1 beta dopamine receptor antibody
    • D1B dopamine receptor antibody
    • D1beta dopamine receptor antibody
    • D5 dopamine receptor antibody
    • DBDR antibody
    • Dopamine D5 receptor antibody
    • Dopamine receptor D1B antibody
    • dopamine receptor D5 antibody
    • DRD 1B antibody
    • DRD 5 antibody
    • DRD1B antibody
    • DRD1L2 antibody
    • DRD5 antibody
    • DRD5_HUMAN antibody
    • MGC10601 antibody
    see all

Anti-Dopamine Receptor D5 antibody 图像

  • Ab32620, at a 1/50 dilution, staining Dopamine Receptor D5 in formalin fixed paraffin embedded human brain tissue by Immunohistochemistry.
  • ICC/IF image of ab32620 stained SKNSH cells. The cells were 4% formaldehyde (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab32620, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899 Dylight 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Dopamine Receptor D5 antibody (ab32620)参考文献

ab32620 has not yet been referenced specifically in any publications.

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