Anti-Dopamine beta Hydroxylase抗体(ab27956)

概述

  • 产品名称
    Anti-Dopamine beta Hydroxylase抗体
    参阅全部 Dopamine beta Hydroxylase 一抗
  • 描述
    羊多克隆抗体to Dopamine beta Hydroxylase
  • 特异性
    ab27956 recognises Dopamine ß-Hydroxylase.
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Rabbit, Cow, Human, Monkey
  • 免疫原

    Synthetic peptide from the C-terminal region of human DBH.

  • 阳性对照
    • Human adrenal medulla lysate

性能

应用

Our Abpromise guarantee covers the use of ab27956 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 68 kDa.
Dot blot 1/1000.

靶标

  • 功能
    Conversion of dopamine to noradrenaline.
  • 通路
    Catecholamine biosynthesis; (R)-noradrenaline biosynthesis; (R)-noradrenaline from dopamine: step 1/1.
  • 疾病相关
    Defects in DBH are the cause of dopamine beta-hydroxylase deficiency (DBH deficiency) [MIM:223360]; also known as norepinephrine deficiency or noradrenaline deficiency. This disorder is characterized by profound deficits in autonomic and cardiovascular function, but apparently only subtle signs, if any, of central nervous system dysfunction.
  • 序列相似性
    Belongs to the copper type II ascorbate-dependent monooxygenase family.
    Contains 1 DOMON domain.
  • 细胞定位
    Cytoplasmic vesicle > secretory vesicle lumen. Cytoplasmic vesicle > secretory vesicle > chromaffin granule lumen and Cytoplasmic vesicle > secretory vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • dbh antibody
    • DBM antibody
    • Dopamine beta hydroxylase antibody
    • Dopamine beta monooxygenase antibody
    • Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody
    • Dopamine beta-monooxygenase antibody
    • DOPO_HUMAN antibody
    • OTTHUMP00000022501 antibody
    • Soluble dopamine beta-hydroxylase antibody
    see all

Anti-Dopamine beta Hydroxylase antibody 图像

实验方案

Anti-Dopamine beta Hydroxylase antibody (ab27956)参考文献

ab27956 has not yet been referenced specifically in any publications.

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