Anti-Dopamine beta Hydroxylase抗体[8.F.304] (ab31126)

概述

  • 产品名称Anti-Dopamine beta Hydroxylase抗体[8.F.304]
    参阅全部 Dopamine beta Hydroxylase 一抗
  • 描述
    小鼠单克隆抗体[8.F.304] to Dopamine beta Hydroxylase
  • 经测试应用适用于: ELISA, ICC, WB, RIDmore details
  • 种属反应性
    与反应: Rat
    不与反应: Mouse, Rabbit, Guinea pig, Cat, Human
  • 免疫原

    Full length protein (Rat)

性能

应用

Our Abpromise guarantee covers the use of ab31126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
ICC Use at an assay dependent dilution.
WB Use at an assay dependent dilution.
RID Use at an assay dependent dilution.

靶标

  • 功能Conversion of dopamine to noradrenaline.
  • 通路Catecholamine biosynthesis; (R)-noradrenaline biosynthesis; (R)-noradrenaline from dopamine: step 1/1.
  • 疾病相关Defects in DBH are the cause of dopamine beta-hydroxylase deficiency (DBH deficiency) [MIM:223360]; also known as norepinephrine deficiency or noradrenaline deficiency. This disorder is characterized by profound deficits in autonomic and cardiovascular function, but apparently only subtle signs, if any, of central nervous system dysfunction.
  • 序列相似性Belongs to the copper type II ascorbate-dependent monooxygenase family.
    Contains 1 DOMON domain.
  • 细胞定位Cytoplasmic vesicle > secretory vesicle lumen. Cytoplasmic vesicle > secretory vesicle > chromaffin granule lumen and Cytoplasmic vesicle > secretory vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • dbh antibody
    • DBM antibody
    • Dopamine beta hydroxylase antibody
    • Dopamine beta monooxygenase antibody
    • Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody
    • Dopamine beta-monooxygenase antibody
    • DOPO_HUMAN antibody
    • OTTHUMP00000022501 antibody
    • Soluble dopamine beta-hydroxylase antibody
    see all

Anti-Dopamine beta Hydroxylase antibody [8.F.304] (ab31126)参考文献

This product has been referenced in:
  • Coll M  et al. Down-regulation of genes related to the adrenergic system may contribute to splanchnic vasodilation in rat portal hypertension. J Hepatol 49:43-51 (2008). WB ; Rat . Read more (PubMed: 18457899) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab31126.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"