Anti-DOPA Decarboxylase抗体(ab32587)

概述

  • 产品名称Anti-DOPA Decarboxylase抗体
    参阅全部 DOPA Decarboxylase 一抗
  • 描述
    兔多克隆抗体to DOPA Decarboxylase
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Sheep, Rabbit, Guinea pig, Cow, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to amino acids from the N terminus of DOPA Decarboxylase (Human) conjugated to KLH.

  • 阳性对照
    • Bovine adrenal medulla lysate.

性能

应用

Our Abpromise guarantee covers the use of ab32587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 55 kDa (predicted molecular weight: 54 kDa).

靶标

  • 功能Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
  • 通路Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2.
  • 疾病相关Defects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) [MIM:608643]. AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.
  • 序列相似性Belongs to the group II decarboxylase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AADC antibody
    • Aromatic L Amino Acid Decarboxylase antibody
    • Aromatic-L-amino-acid decarboxylase antibody
    • DDC antibody
    • DDC_HUMAN antibody
    • DOPA decarboxylase (aromatic L-amino acid decarboxylase) antibody
    • DOPA decarboxylase antibody
    see all

Anti-DOPA Decarboxylase antibody 图像

Anti-DOPA Decarboxylase antibody (ab32587)参考文献

ab32587 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Regarding ab32587, I apologize that I can only offer you a range in which to expect the concentration to fall. This product is not formulated based solely on concentration. The signal strength (in QC-WB) is a much more ...

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